Disodium guanylate

Disodium 5'-guanylate (a 5'-ribonucleotide).

Flavor enhancer synergistic with glutamates in savory snacks and soups.

Metabolized to purines. Contributes to purine intake.

People with gout or hyperuricemia may need to moderate purine intake. Generally safe at food levels.

Permitted in EU Annex II; often used with E 631 at lower combined levels.

Disodium guanylate is a permitted food additive in the U.S. under 21 CFR 172.530 as a flavor enhancer. It is often combined with MSG and disodium inosinate for synergistic umami effects. It contributes to dietary purine intake, relevant for people with gout.

Category-specific limits in Annex II Part E.

Not allocated.